PIK-III - CAS# 1383716-40-2 6053 is a potent and selective

is a potent and selective Wnt signaling pathway inhibitor discovered by a cell-based screening

287(13):9742-52

74(15):4170-82

Bromosporine (1 µM) accelerates FRAP recovery of BRD4 and CREBBP

Smiles: CCO

PIK-III - CAS# 1383716-40-2 6053 is a potent and selectivePIK III, also known as VPS34 IN2, CAS No. 1383716 40 2, is a VPS34 inhibitor which blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. PIK III binds a unique hydrophobic pocket not present in related kinases such as PI(3)K. PIK III acutely inhibits autophagy and de novo lipidation of LC3, and leads to the stabilization of autophagy substrates. . Product information CAS Number: 1383716 40 2 Molecular