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The affinity of Eptapirone (F11440) for 5-HT1Abinding sites (pKi
PubMed PMID: 26228681
438190-29-5
Co-culture of hepatocellular carcinoma cells and human umbilical endothelial cells damaged by SU11274
Pre-treatment of AML cells with IPI-145 inhibits both adhesion and migration of AML blasts to bone marrow stromal cells
SR9011 - REV-ERB Agonist. CAS# 1379686-29-9 Catalog No.:M66049-2S The affinity of Eptapirone (F11440)SR9011, CAS No. 1379686 29 9, is a potent and specific synthetic REV ERB agonist that binds to REV ERB with an EC50 ~790 nM and REV ERB with EC50 ~560 nM. It also has good in vivo plasma brain exposure. The nuclear receptors REV ERB and REV ERB play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock
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