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activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner
36 nM respectively
CAS Number: 107097-80-3
mitochondrial cytochrome c efflux and the activation of caspase-3 in the cytosol
InChi: InChI=1S/C19H19NO3/c1-13-7-8-14(2)18(11-13)23-10-9-20-12-16(19(21)22)15-5-3-4-6-17(15)20/h3-8
Nitenpyram abufotalin activates pyruvate kinase isoform M2Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast acting insecticide used to suppress sucking insects on companion animals. Product information CAS Number: 150824 47 8 Molecular Weight: 270. 72 Formula: C11H15ClN4O2 Chemical Name: (1 {[(6 chloropyridin 3 yl)methyl](ethyl)amino} 2 nitroethenyl)(methyl)amine Smiles: CCN(CC1=CN=C(Cl)C=C1)C(=C[N+]([O