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YM155 shows 80% TGI at a dose of 5 mg/kg in PC-3 orthotopic xenografts[1]
and is being developed by Ignyta
Water: 1 mg/mL(2
24)25/h2-6
5-fluoruracil
Triptonide - CAS# 38647-11-9 60313 YM155 shows 80% TGI atTriptonide, CAS No. 38647 11 9, is a Wnt catenin inhibitor. Triptonide can effectively inhibit canonical Wnt catenin signaling by targeting the downstream C terminal transcription domain of catenin or a nuclear component associated with catenin. It also effectively induced apoptosis of Wnt dependent cancer cells, supporting the therapeutic potential of triptonide. Product information CAS Number: 38647 11 9 Molecular Weight: 358. 39 Formula: C20H22O6
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