Bomedemstat ditosylate Catalog No.:M33503-C CAS Number: 2550398-89-3

CAS Number: 2550398-89-3

Chemical Name: 3-methoxybenzo[b]1

InChiKey: QNNBMSGFNQRUEH-PQQSRXGVSA-N

Thalidomide-O-amido-C6-NH2 hydrochloride

Acute (5 g/kg) and chronic (25 and 250 mg/kg) toxicology studies in uninfected mice show that

Bomedemstat ditosylate Catalog No.:M33503-C CAS Number: 2550398-89-3Bomedemstat, also known as IMG 7289, is a lysine specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndrome, and Myelofibrosis. IMG 7289 selectively inhibited proliferation and induced apoptosis of JAK2 V617F cells by concomitantly increasing expression and methylation of p53, and, independently, the pro apoptotic factor PUMA and by